The color and pattern of the bed linen should be an integral part of the decor and design. You can bring a touch of color to a dull, boring monochromatic room with a funky bed linen. Or you can accentuate the color scheme with a bolder, darker shade of the whole scheme.
If your room is painted bold and bright, tone down on the edgy with the bed linen. Choose a more subdued, muted shade here as well as with the decor. This will avoid creating a cluttered, chaotic look by balancing the intensity.
If your room is painted a plain, pastel color, or all-white, choose bed covers with a little more pop. You could also try bold patterns. This will create an interesting focal point for the eyes.
Another option you can try is an all-white linen. This is one of the safest and classiest options. Not only will the linen not fade with time (like other colored covers), but it will also lend the room a touch of elegance.
If you choose to try the last option, keep in mind, you can also try colored pillows covers for an interesting look.